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In health and social sciences, it is critically important to identify subgroups of the study population where a treatment has notable heterogeneity in the causal effects with respect to the average treatment effect. Data-driven discovery of heterogeneous treatment effects (HTE) via decision tree methods has been proposed for this task. Despite its high interpretability, the single-tree discovery of HTE tends to be highly unstable and to find an oversimplified representation of treatment heterogeneity. To accommodate these shortcomings, we propose Causal Rule Ensemble (CRE), a new method to discover heterogeneous subgroups through an ensemble-of-trees approach. CRE has the following features:

  1. provides an interpretable representation of the HTE; 2) allows extensive exploration of complex heterogeneity patterns; and 3) guarantees high stability in the discovery. The discovered subgroups are defined in terms of interpretable decision rules, and we develop a general two-stage approach for subgroup-specific conditional causal effects estimation, providing theoretical guarantees.

References

Bargagli-Stoffi, F. J., Cadei, R., Lee, K. and Dominici, F. (2023). Causal rule ensemble: Interpretable Discovery and Inference of Heterogeneous Treatment Effects,arXiv preprint arXiv:2009.09036

Author

Naeem Khoshnevis

Daniela Maria Garcia

Riccardo Cadei

Kwonsang Lee

Falco Joannes Bargagli Stoffi